Professor & Doctor of Pediatrics Chief Physician of Pediatrics Post-doctoral Research Fellow of Medical Genetics Present Position Vice President of Hainan Medical University Director of National Health Commission Key Laboratory of Tropical Disease Control Doctoral Supervisor Other Position Former Chairman of Child Health Committee, Chinese Medical Doctor Association Standing Committee Member of Pediatric Branch and Vice Chairman of Special Committee on Early Childhood Development, Chinese Medical Association Deputy Head of Child Health Science Group, Pediatric Branch, Chinese Medical Association Served in the Editorial Boards of Multiple Magazines such as "Chinese Journal of Pediatrics" "Journal of Clinical Pediatrics" et al. Expert Enjoying Special Government Allowance under the State Council Prof. (Dr.) Wei Xiang was long-term engaged in Pediatric Clinic & Children Health Science, and quite accomplished in the aspect of pediatric nutrition. He used to be the editor-in-chief for 3 academic monographs. As the first author (or corresponding author), he had published more than 100 papers in authoritative journals in related research fields. He also presided 4 projects funded by the National Natural Science Foundation of China. Prof. (Dr.) Xiang had won the Hainan Provincial Science and Technology Progress Award for first prize prize as the first complete person for twice. He had formulated 5 guidelines of the prevention and treatment for the pediatric nutritional disease.

Executive vice president of West China Second University Hospital, Sichuan University Vice Chairman of the Pediatric Society of Chinese Medical Association Vice Chairman of the Society of Perinatal Medicine of Chinese Medical Association Vice Chairman of the Pediatricians Society of Chinese Medical Doctor Association Awarded: National Science Fund for Distinguished Young Scholars & Leader of Innovative Team of Changjiang Scholars Program of the Ministry of Education of China Editor-in-Chief of Chinese Journal of Obstetrics & Gynecology and Pediatrics

Education: 2005.02-2005.04 Senior Visiting Scholar, Department of Pediatrics, University of Utah. 1992.09-1994.07 Ph.D. (Pediatric Cardiology), Jichi Medical University, Japan. 1985.09-1988.07 Master Degree (Pediatrics), West China Medical University, China. 1980.09-1985.07 Bachelor Degree (Clinical Medicine), West China Medical University, China. Research Interest: I have been specializing in Pediatric Intensive Care Medicine for nearly 30 years. I am good at diagnosis and treatment of common critical illness, especially sepsis, septic shock and ARDS. My primary research of interest is sepsis-induced myocardial dysfunction in children, and I have performed both clinical and basic researches for many years. Administrative Positions: 1. The Director of Department of Pediatrics, the Director of Department of Pediatric Emergency Medicine, Shengjing Hospital of China Medical University. 2. The Director of Clinical Research Center of Children's Health and Disease of Liaoning Province. 3. The Director of Editorial Department of Chinese Pediatric Emergency Medicine. 4. The Member of the Standing Committee of Pediatrics of Chinese Medical Association, the Chairman of the First Aid Group of Pediatrics of Chinese Medical Association, and Vice Chairman of Pediatric Critical Care Medicine of Chinese Medical Association. 5. The Chairman of Pediatrician of Liaoning Medical Association, and Chairman of Pediatrics of Liaoning Medical Association. 6. The Chairman of Pediatric Critical Care Group of Inner Mongolia and Northeast area in China. Managed the project (PI) 1. Construction of a platform for children's disease and health center. Supported by Liaoning province key research and development plan guidance plan project NO. 2017225003 Total costs for project period: 500,000 RMB Project period: 1/1/18-12/31/20 2. Liaoning pediatric disease clinical medical research center. Supported by Local professional technology innovation platform NO. 2018108001 Total costs for project period: 500,000 RMB Project period: 1/1/18-12/31/20 3. The role and regulation mechanism of β3-adrenoceptor in the model of sepsis-induced myocardial depression in rats. Supported by the Natural Science Foundation of China NO. 81372039 Total costs for project period: 700,000 RMB Project period: 1/1/14-12/31/17 4. The regulation of autophagy in sepsis-induced myocardial depression in rats. Supported by Liaoning planned project NO. 2014225017 Total costs for project period: 600,000 RMB Project period: 1/1/13-12/31/17 5. Changes of β-AR signaling pathway and cardiac dysfunction in sepsis rats Supported by Natural Science Foundation of Liaoning province NO. [2005]08 Total costs for project period: 50,000R MB Project period: 1/1/05-12/31/08 6. Mechanism of systemic inflammatory response syndrome and multiple organ failure in critically ill children Supported by Social Science Development Funding of Liaoning province NO. [2001]88 Total costs for project period: 50,000 RMB Project period: 1/1/01-12/31/03 Selected Publications (Corresponding author) 1. Wang W, Yang N, Wen R, Liu CF, Zhang TN. Long Noncoding RNA: Regulatory Mechanisms and Therapeutic Potential in Sepsis. Front Cell Infect Microbiol. 2021. 11:563126. 2. Zhang TN, Wen R, Yang N, Liu CF. Comparative transcriptome analysis of transcripts of uncertain coding potential in septic myocardial depression. BMC Cardiovasc Disord. 2021. 21(1):166. 3. Zhang TN, Wang W, Yang N, Huang XM, Liu CF. Regulation of Glucose and Lipid Metabolism by Long Non-coding RNAs: Facts and Research Progress. Front Endocrinol (Lausanne). 2020.11:457. 4. Zhang TN, Goodwin JE, Liu B, Li D, Wen R, Yang N, Xia J, Zhou H, Zhang T, Song WL, Liu CF. Characterization of Long Noncoding RNA and mRNA Profiles in Sepsis-Induced Myocardial Depression. Mol Ther Nucleic Acids. 2019. 17:852-866. 5. Zhang TN, Yang N, Goodwin JE, Mahrer K, Li D, Xia J, Wen R, Zhou H, Zhang T, Song WL, Liu CF. Characterization of Circular RNA and microRNA Profiles in Septic Myocardial Depression: a Lipopolysaccharide-Induced Rat Septic Shock Model. Inflammation. 2019. 42(6):1990-2002. 6. Zhang TN, Li D, Wu QJ, Xia J, Wen R, Chen XC, Yang N, Chen YL, Hang YH, Liu CF. Exposure to nitrogen oxide in the first trimester and risk of cardiovascular-related malformations: a dose-response meta-analysis of observational studies. Biomed Res Int. 2018; 2018: 1948407. 7. Xu W, Chen YL, Zhao Y, Wang LJ, Li JJ, Liu CF. A Clinical Study of Toxication Caused by Carbamazepine Abuse in Adolescents. Biomed Res Int. 2018; 2018:3201203. 8. Yang N, Shi XL, Zhang BL, Jian Rong, Zhang TN, Xu W, Liu CF The Trend of β3-Adrenergic Receptor in the Development of Septic Myocardial Depression: A Lipopolysaccharide-Induced Rat Septic Shock Model. Cardiology. 2018;139(4):234–244. 9. Yang N, Wu L, Zhao Y, Zou N, Liu CF. MicroRNA-320 involves in the cardioprotective effect of insulin against myocardial ischemia by targeting survivin. Cell Biochem Funct. 2018,36(3):166-171. 10. Zhang B, Liu CF, Yang N, Wang X. A comparative study of changes of autophagy in rat models of CLP versus LPS induced sepsis. Exp Ther Med. 2017;14(3):2194–2200. 11. Zhang TN, Li D, Xia J, Wu QJ, Wen R, Yang N, Liu CF. Non-coding RNA: a potential biomarker and therapeutic target for sepsis. Oncotarget. 2017;8(53):91765–91778. 12. Liu CF, Xiong X, Xu W, Sun J, Wang L, Li J. Serotypes and patterns of antibiotic resistance in strains causing invasive pneumococcal disease in children less than 5 years of age. PLoS One. ;8(1): e54254. 13. Xu W, Liu CF, Zhao Y, Li JJ, Wang LJ, Wen GF, Liu Z. Findings in children severely infected with a novel influenza A virus of swine origin: pulmonary imaging. World Journal of Pediatrics, 2012, 8(3):240-246.

Secretary of the Party Committee of Shanghai Jiao Tong University School of Medicine Professor of Developmental and Behavioral Pediatrics and director of Early Childhood Development Research Center in National Children’s Medical Center Vice director of Ministry of Education Key Laboratory of Environment and Child Health Chair of the Children's Health Committee of Chinese Medical Doctor Association Chair of Chinese Child Health Care Association Vice chairman of the Chinese Preventive Medicine Society Advisory board of Early Child Development Program in UNICEF China

王宝西 教授 主任医师 教授 博士生导师 中华医学会儿科学分会消化学组副组长 中华医学会儿科学分会常委 中华医学会消化学分会儿科学组组长 中国医师协会儿科分会常委 中华儿科医师继续教育学会主任委员 中华医学会陕西儿科学会名誉主任委员 中国医师协会内镜医师分会儿科消化内镜专业委员会主任委员 2017年荣获全国儿科医师奖

Professor Song Hongmei is the Director of Pediatrics and doctoral supervisor at Peking Union Medical College (PUMC)Hospital, Chinese Academy of Medical Sciences (CAMS). After completing her undergraduate and master’s education in China, Dr. Song went to Japan and received her Ph.D. degree from the Department of Second Internal Medicine, University of Occupational & Environmental Health, Japan. She returned to the Department of Pediatrics at PUMC Hospital in 2000 and served as attending physician, associate professor, professor, deputy director since 2003, and director since 2009. Dr. Song is currently a standing Committee member of the Pediatric Commission of Chinese Medical Association and Chairman of Immunology Division, President of Beijing Branch of the Chinese Medical Association and Chairman of Rheumatology and Immunology Division, Chairman of Rare Diseases Medication Working Committee of Chinese Pharmacists Association, Deputy head of Pediatric Group of Expert Committee on Clinical Rational Drug Use of National Health Commission, Deputy editor-in-chief of Chinese Journal of Pediatrics, Executive deputy editor-in-chief of Chinese Journal of Evidence Based Pediatrics. She is also an editorial board member and reviewer of many professional journals. Her research interests are in pediatric rheumatic and immunologic diseases. Recently, her research has focused on autoinflammatory diseases (AIDs), especially type I interferonopathy, which is a type of primary immune disorder. Using gene trap high-throughput sequencing and next-generation sequencing (NGS) combined with Sanger sequencing verification, she and her research group validated several AIDs, some of which are the first cases in China, including STING-associated vasculopathy with onset in infancy (SAVI), pyogenic sterile arthritis, pyoderma gangrenosum, acne (PAPA), and joint contractures, muscle atrophy, microcytic anemia, and panniculitis-induced childhood onset lipodystrophy (JMP syndrome). Dr. Song has chaired or participated in several research grants and has published more than 150 academic papers. Dr. Song has also received the third prize of Beijing Medical Science and Technology Progress Award and other awards.

主任医师，教授，博士生导师。 复旦大学附属儿科医院副院长，上海市出生缺陷防治重点实验室副主任 中国医师协会临床遗传医师分会副会长，中华医学会罕见病分会常委，中华医学会儿科学分会新生儿学组组长，上海医学会罕见病分会侯任主委，上海医师协会儿科分会会长。 承担国家自然科学基金重点项目、重点国际合作项目等 10项，在《Nature 》、《JAMA Pediatric》、《Developmental Cell》等专业SCI论文128篇 入选教育部新世纪优秀人才计划、上海市领军人才和上海市优秀学术带头人 获得上海科技进步一等奖和中华医学奖等。